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Product Info Summary
| SKU: | A04486 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-KIF4A Antibody
SKU/Catalog Number
A04486
Size
100ul
Form
Liquid
Description
Boster Bio Anti-KIF4A Antibody catalog # A04486. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KIF4A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04486)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human KIF4A
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04486 is reactive to KIF4A in Human
Applications
A04486 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
139.881kDa
Background of KIF4A
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Yeh E.T.H., Gene 248:1-14(2000).
Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Wiemann S., Genome Res. 11:422-435(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:40000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-KIF4A Antibody A04486
Western Blot (WB) analysis of specific cells using KIF4A polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For KIF4A (Source: Uniprot.org, NCBI)
Gene Name
KIF4A
Full Name
Chromosome-associated kinesin KIF4A
Weight
139.881kDa
Superfamily
TRAFAC class myosin-kinesin ATPase superfamily
Alternative Names
chromokinesin-A; chromosome-associated kinesin KIF4A; FLJ12530; FLJ12655; FLJ14204; FLJ20631; HSA271784; KIF4G1; KIF4KIF4-G1; kinesin family member 4A KIF4A KIF4, KIF4G1, MRX100 kinesin family member 4A chromosome-associated kinesin KIF4A|chromokinesin-A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KIF4A, check out the KIF4A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KIF4A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KIF4A Antibody (A04486)
Hello CJ!
No publications found for A04486
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