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Product Info Summary
| SKU: | A03789 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-KIR2DS2 Antibody
SKU/Catalog Number
A03789
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-KIR2DS2 Antibody (Catalog # A03789). Tested in ELISA, WB, IF, ICC applications. This antibody reacts with Human.
Storage & Handling
KIR2DS2 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-KIR2DS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03789)
Host
Rabbit
Contents
KIR2DS2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.
Cross-reactivity
KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
Reactive Species
A03789 is reactive to KIR2DS2 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
33.5 kDa
Background of KIR2DS2
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03789 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KIR2DS2 antibody can be used for detection of KIR2DS2 by Western blot at 1 - 2 μg/ml. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KIR2DS2 in 293 cell lysate with KIR2DS2 antibody at (A) 1 and (B) 2 μg/ml.
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Immunocytochemistry of KIR2DS2 in Hek293 cells with KIR2DS2 antibody at 5 μg/mL.
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Immunofluorescence of KIR2DS2 in 293 cells with KIR2DS2 antibody at 20 μg/ml.
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Immunofluorescence of KIR2DS2 in Hek293 cells with KIR2DS2 antibody at 20 μg/mL.
Green: KIR2DS2 Antibody (A03789)
Blue: DAPI staining
Specific Publications For Anti-KIR2DS2 Antibody (A03789)
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