Anti-Kv1.4/KCNA4 Antibody Picoband®

Product Name

Anti-Kv1.4/KCNA4 Antibody Picoband®

View all KCNA4 Antibodies

SKU/Catalog Number

PA2297

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Kv1.4/KCNA4 Antibody catalog # PA2297. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kv1.4/KCNA4 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2297)

Host

Rabbit

Contents

Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Kv1.4, different from the related mouse and rat sequences by one amino acid.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2297 is reactive to KCNA4 in Human, Mouse, Rat

Observed Molecular Weight

70 kDa

Calculated molecular weight

73.3 kDa

Background of KCNA4

Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2297 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Brain Tissue, HY1080Whole Cell, PANC Whole Cell, U87 Whole Cell, SHG Whole Cell

Validation Images & Assay Conditions

See full target information KCNA4

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