Anti-Laminin 2 alpha/LAMA2 Antibody

Product Name

Anti-Laminin 2 alpha/LAMA2 Antibody

View all Laminin alpha 2 Antibodies

SKU/Catalog Number

PA2160

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Laminin 2 alpha/LAMA2 Antibody catalog # PA2160. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Laminin 2 alpha/LAMA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2160)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Laminin 2 alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2160 is reactive to LAMA2 in Human, Mouse, Rat

Applications

PA2160 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

14 kDa

Calculated molecular weight

343.905kDa

Background of Laminin alpha 2

Laminin, alpha-2, also known as LAMA2, is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

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Anti-Laminin 2 alpha antibody, PA2160, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: A549 Cell Lysate
Lane 3: PANC Cell Lysate

Gene/Protein Information For LAMA2 (Source: Uniprot.org, NCBI)

Alternative Names

LAMA2; Laminin alpha 2; Laminin M chain; laminin subunit alpha-2; laminin, alpha 2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; LAMM; LAMMLaminin-4 subunit alpha; Merosin heavy chain; Merosin LAMA2 LAMM, MDC1A laminin subunit alpha 2 laminin subunit alpha-2|laminin M chain|laminin, alpha 2|laminin-12 subunit alpha|laminin-2 subunit alpha|laminin-4 subunit alpha|merosin heavy chain|mutant laminin subunit alpha 2

For more info on LAMA2, check out the LAMA2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LAMA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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