Anti-LAMTOR1 Antibody

Product Name

Anti-LAMTOR1 Antibody

View all LAMTOR1 Antibodies

SKU/Catalog Number

A06290

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-LAMTOR1 Antibody (Catalog # A06290). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

LAMTOR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-LAMTOR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06290)

Host

Rabbit

Contents

LAMTOR1 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Rabbit polyclonal LAMTOR1 antibody was raised against a 17 amino acid peptide near the amino terminus of human LAMTOR1 . The immunogen is located within the first 50 amino acids of LAMTOR1.

Cross-reactivity

LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins.

Reactive Species

A06290 is reactive to LAMTOR1 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

17.7 kDa

Background of LAMTOR1

LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06290 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

LAMTOR1 antibody can be used for detection of LAMTOR1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information LAMTOR1

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