Anti-liver FABP/FABP1 Antibody
Rabbit IgG polyclonal antibody for Fatty acid-binding protein, liver(FABP1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Anti-liver FABP/FABP1 Antibody Info At A Glance
|Reactivity:||Human, Mouse, Rat|
NudE Neurodevelopment Protein 1-Like 1 also known as NDEL1 is a coiled-coil protein which participates in multiple processes as well as cytoskeletal
|Product Name||Anti-liver FABP/FABP1 Antibody
See all FABP1/L-FABP primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for L FABP/FABP1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. L FABP/FABP1 information: Molecular Weight: 14208 MW; Subcellular Localization: Cytoplasm.|
|Cite This Product||Anti-liver FABP/FABP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1229-1)|
|Similar Products From
|Anti-liver FABP/FABP1 Antibody may replace the following items: sc 16064|sc 16065|sc 271591|sc 374537|sc 50380.|
|Reactivity/Species||Human, Mouse, Rat|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human liver FABP(16-31aa EAFMKAIGLPEELIQK), different from the related mouse sequence by two amino acids.|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For FABP1 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||2168|
|Species Of This Entry||Human|
|Protein Name||Fatty acid-binding protein, liver|
|Alternative Names||FABP1/L-FABP|FABP1; FABPL; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; LFABP; L-FABP; L-FABPFatty acid-binding protein 1; Liver-type fatty acid-binding protein|
|Post Tranlational Modifications||Oxidation; Carboxylation; Phosphorylation; Reduction; Biotinylation; Acylation; Iodination|
|Gene Location||2p11.2, on Chromasome 2, gene sequence: NC_000002.12 (88122982..88128062, complement)|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For FABP1 (Source: Uniprot.org, NCBI)
|Protein Function||Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).|
|Research Areas||Breast Cancer; Cancer; Cholesterol Metabolism; Diabetes Research; Lipid and Metabolism|
|Related Diseases||Fatty Liver; Kidney Diseases; Injury To Kidney; Malignant Neoplasms; Acute Kidney Injury; Liver Carcinoma; Neoplasms; Diabetes Mellitus; Obesity; Chronic Kidney Disease; Proteinuria Of Undiagnosed Cause; Inflammation; Liver Neoplasms; Kidney Failure, Chronic; Carcinoma; Adenoma; Steatosis; Diabetes Mellitus, Non-insulin-dependent; Diabetic Nephropathy; Ischemia|
|Related Pathways||Transport; Excretion; Localization; Glomerular Filtration; Fatty Acid Transport; Lipid Binding; Fatty Acid Oxidation; Secretion; Cell Differentiation; Cell Proliferation; Intracellular Transport; Pathogenesis; Cholesterol Homeostasis; Aging; Cell Growth; Reverse Transcription; Cell Migration; Lipid Homeostasis; Sterol Esterification; Lactation|
|Background||Fatty acid binding protein 1, liver, also known as FABP1 or FABPL, is a human gene locating at 2p11. FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind free fatty acids, their CoA derivatives, bilirubin, organic anions, and other small molecules. FABP1 and FABP6(the ileal fatty acid binding protein) are also able to bind bile acids. It is though that FABPs roles include fatty acid uptake, transport, and metaboism. The liver form of FABP may be identical to the major liver protein-1(Lvp-1), which is encoded by a gene situated within 1 cM of Ly-2.|
|Scientific References||PMID: 3838309 by Chan L., et al. Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.|
PMID: 3838313 by Lowe J.B., et al. Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins.
Our Boster Quality Guarantee for Anti-liver FABP/FABP1 Antibody covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Kidney Tissue Lysate
Lane 3: HELA Cell Lysate
Lane 4: NEURO Cell Lysate
Lane 5: SMMC Cell Lysate
IHC(P): Rat Liver Tissue
IHC(P): Human Liver Cancer Tissue
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
Other Recommended Resources
Here are featured tools and databases that you might find useful.
Order Product (PA1229-1)
Domestically in USA and Canada, ships next business day if available in stock.
Note: sample size takes longer to process, average 5-7 days.
All Boster antibodies and ELISA kits are guaranteed to meet the specifications on the data sheet.See Details
Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.Download Free PDFs Now
Guaranteed product quality
We promise all of our products perform as described in datasheets.