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Product Info Summary
| SKU: | M00438-4 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-LMNA Antibody
SKU/Catalog Number
M00438-4
Size
50 µl
Description
Boster Bio Anti-LMNA Antibody (Catalog # M00438-4). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-LMNA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00438-4)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1073CT3.1.3
Isotype
IgG1,k
Immunogen
This antibody is generated from a mouse immunized with a recombinant protein.
Reactive Species
M00438-4 is reactive to LMNA in Human, Mouse, Rat
Calculated molecular weight
74.1 kDa
Background of LMNA
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00438-4 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:4000
Validation Images & Assay Conditions
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All lanes : Anti-LMNA antibody at 1:4000 dilution
Lane 1: Hela whole cell lysate
Lane 2: C6 whole cell lysate
Lane 3: L929 whole cell lysate
Lane 4: NIH/3T3 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 74, 65 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Specific Publications For Anti-LMNA Antibody (M00438-4)
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