Anti-LPIN1 Antibody

Lipin 1 antibody

Boster Bio Anti-LPIN1 Antibody (Catalog # A02467). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A02467
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-LPIN1 Antibody

View all Lipin 1 Antibodies

SKU/Catalog Number

A02467

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-LPIN1 Antibody (Catalog # A02467). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

LPIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-LPIN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02467)

Host

Rabbit

Contents

LPIN Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

LPIN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LPIN1. The immunogen is located within the last 50 amino acids of LPIN1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

LPIN1 antibody is human and mouse reactive. At least four isoforms of LPIN1 are known to exist.

Reactive Species

A02467 is reactive to LPIN1 in Human, Mouse, Rat

Applications

A02467 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Background of Lipin 1

LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2). Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

LPIN1 antibody can be used for detection of LPIN1 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For LPIN1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q14693

Gene ID

23175

Gene Name

LPIN1

Full Name

Phosphatidate phosphatase LPIN1

Weight

98.664kDa

Superfamily

lipin family

Alternative Names

DKFZp781P1796; EC 3.1.3.18; EC 3.1.3.4; EC 5.4.2.7; KIAA0188phosphatidate phosphatase LPIN1; Lipin 1; lipin-1; LPIN1; PAP1 LPIN1 PAP1 lipin 1 phosphatidate phosphatase LPIN1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LPIN1, check out the LPIN1 Infographic

LPIN1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LPIN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $404

SKU:A02467

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Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

In stock
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A02467
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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