Anti-LTK Antibody

Product Name

Anti-LTK Antibody

View all LTK Antibodies

SKU/Catalog Number

A04217

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-LTK Antibody (Catalog # A04217). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LTK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04217)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human LTK.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04217 is reactive to LTK in Human, Mouse

Reconstitution

Observed Molecular Weight

Calculated molecular weight

91681 MW

Background of LTK

Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A04217 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Positive Control

Validation Images & Assay Conditions

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Western blot analysis of extracts from Jurkat cells, using LTK antibody A04217.

Gene/Protein Information For LTK (Source: Uniprot.org, NCBI)

Alternative Names

EC 2.7.10.1; leukocyte receptor tyrosine kinase; leukocyte tyrosine kinase receptor; leukocyte tyrosine kinase; LTK; TYK1; TYK1Protein tyrosine kinase 1 LTK TYK1 leukocyte receptor tyrosine kinase leukocyte tyrosine kinase receptor|protein tyrosine kinase 1

For more info on LTK, check out the LTK Infographic

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In this infographic, you will see the following information for LTK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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