Anti-LXR alpha/NR1H3 Antibody

Boster Bio Anti-LXR alpha/NR1H3 Antibody catalog # PA1246-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PA1246-1
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-LXR alpha/NR1H3 Antibody

See all NR1H3 products

SKU/Catalog Number

PA1246-1

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-LXR alpha/NR1H3 Antibody catalog # PA1246-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LXR alpha/NR1H3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1246-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha (371-385aa NVQDQLQVERLQHTY), identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1246-1 is reactive to NR1H3 in Human, Mouse, Rat

Applications

PA1246-1 is guaranteed for WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For NR1H3 (Source: Uniprot.Org, NCBI)

Uniprot ID

Q13133

Gene ID

10062

Gene Name

NR1H3

Full Name

Oxysterols receptor LXR-alpha

Weight

50.396kDa

Superfamily

nuclear hormone receptor family

Alternative Names

alpha; Liver X receptor alpha; liver X receptor-alpha; LXR alpha; LXRA; NR1H3; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD-1 NR1H3 LXR-a, LXRA, RLD-1 nuclear receptor subfamily 1 group H member 3 oxysterols receptor LXR-alpha|liver X nuclear receptor alpha variant 1

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on NR1H3, check out the NR1H3 Infographic

NR1H3 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for NR1H3: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1246-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Shang W, Yu X, Wang H, Chen T, Fang Y, Yang X, Zhou P, Nie F, Zhou Q, Zhou J. Mol Med Rep. 2015 Jan;11(1):503-8. Doi: 10.3892/Mmr.2014.2731. Epub 2014 Oct 21. Fibroblast Growth Factor 21 Enhances Cholesterol Efflux In Thp-1 Macrophage-Derived Foam...

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6 Customer Q&As for Anti-LXR alpha/NR1H3 Antibody

Question

We are currently using anti-LXR alpha/NR1H3 antibody PA1246-1 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2020-01-27

Answer

The anti-LXR alpha/NR1H3 antibody (PA1246-1) has not been validated for cross reactivity specifically with goat tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-01-27

Question

I was wanting to use your anti-LXR alpha/NR1H3 antibody for WB for mouse right lobe of liver on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for mouse right lobe of liver identification?

J. Krishna

Verified customer

Asked: 2018-07-27

Answer

It shows on the product datasheet, PA1246-1 anti-LXR alpha/NR1H3 antibody has been tested for WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in mouse right lobe of liver in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2018-07-27

Question

Is a blocking peptide available for product anti-LXR alpha/NR1H3 antibody (PA1246-1)?

Verified Customer

Verified customer

Asked: 2017-06-21

Answer

We do provide the blocking peptide for product anti-LXR alpha/NR1H3 antibody (PA1246-1). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2017-06-21

Question

We are interested in to test anti-LXR alpha/NR1H3 antibody PA1246-1 on mouse right lobe of liver for research purposes, then I may be interested in using anti-LXR alpha/NR1H3 antibody PA1246-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

A. Gonzalez

Verified customer

Asked: 2015-07-13

Answer

The products we sell, including anti-LXR alpha/NR1H3 antibody PA1246-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2015-07-13

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for right lobe of liver using anti-LXR alpha/NR1H3 antibody PA1246-1. Let me know if you need anything else.

V. Anderson

Verified customer

Asked: 2015-03-24

Answer

Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2015-03-24

Question

Is this PA1246-1 anti-LXR alpha/NR1H3 antibody reactive to the isotypes of NR1H3?

E. Taylor

Verified customer

Asked: 2015-02-20

Answer

The immunogen of PA1246-1 anti-LXR alpha/NR1H3 antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha(371-385aa NVQDQLQVERLQHTY), identical to the related rat and mouse sequences. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2015-02-20

Size

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Ships directly to USA and Canada. For other regions, visit our distributors page

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PA1246-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$240.00

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