- Table of Contents
LXRES are DR4-type response components characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake via MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530).
|nuclear hormone receptor family|
|Sequence:||11; NC_000011.10 (47248300..47269033)|
Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
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