Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®

Product Name

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®

View all IGF2R Antibodies

SKU/Catalog Number

PA2182
BA0942 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody catalog # PA2182. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2182)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent), different from the related rat and mouse sequences by one amino acid.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2182 is reactive to IGF2R in Human, Mouse, Rat

Observed Molecular Weight

274 kDa

Calculated molecular weight

274.4 kDa

Background of IGF2R

Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2182 is guaranteed for Flow Cytometry, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Positive Control

WB: human Hela whole cell, human U87 whole cell, human HepG2 whole cell, rat PC-12 whole cell, mouse NIH/3T3 whole cell
FCM: HepG2 cell

Validation Images & Assay Conditions

See full target information IGF2R

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