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Product Info Summary
| SKU: | A08043 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-MAP1 MOAP1 Antibody
SKU/Catalog Number
A08043
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MAP1 MOAP1 Antibody (Catalog # A08043). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
MAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MAP1 MOAP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08043)
Host
Rabbit
Contents
MAP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MAP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1. The immunogen is located within the last 50 amino acids of MAP1.
Reactive Species
A08043 is reactive to MOAP1 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
39.5 kDa
Background of MOAP1
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08043 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 to 4 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MAP-1 in EL4 cell lysate with MAP-1 antibody (IN) at (A) 1, (B) 2, and (C) 4 μg/mL.
Specific Publications For Anti-MAP1 MOAP1 Antibody (A08043)
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