Anti-MEK6/MAP2K6 Antibody

MKK6/MEK6 antibody

Boster Bio Anti-MEK6/MAP2K6 Antibody catalog # PA1921. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA1921
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-MEK6/MAP2K6 Antibody

View all MKK6/MEK6 Antibodies

SKU/Catalog Number

PA1921

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MEK6/MAP2K6 Antibody catalog # PA1921. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MEK6/MAP2K6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1921)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MEK6, identical to the related mouse sequence and different from the related rat sequence by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1921 is reactive to MAP2K6 in Human, Mouse, Rat

Applications

PA1921 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

22-24 kDa

Calculated molecular weight

37.492kDa

Background of MKK6/MEK6

MAP2K6 (Mitogen-activated protein kinase kinase 6), also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene. It is located on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediatedsignal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For MAP2K6 (Source: Uniprot.org, NCBI)

Gene Name

MAP2K6

Full Name

Dual specificity mitogen-activated protein kinase kinase 6

Weight

37.492kDa

Superfamily

protein kinase superfamily

Alternative Names

MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 6; MAPKK6dual specificity mitogen-activated protein kinase kinase 6; MEK6; MEK6MAPKK 6; mitogen-activated protein kinase kinase 6; MKK6; MKK6MEK 6; PRKMK6; PRKMK6protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPKK3; SAPKK3EC 2.7.12.2 MAP2K6 MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 mitogen-activated protein kinase kinase 6 dual specificity mitogen-activated protein kinase kinase 6|MAPK/ERK kinase 6|MAPKK 6|MEK 6|SAPK kinase 3|protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)|stress-activated protein kinase kinase 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAP2K6, check out the MAP2K6 Infographic

MAP2K6 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAP2K6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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7 Customer Q&As for Anti-MEK6/MAP2K6 Antibody

Question

I see that the anti-MEK6/MAP2K6 antibody PA1921 works with WB, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2019-12-13

Answer

You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2019-12-13

Question

See below the WB image, lot number and protocol we used for cervix carcinoma using anti-MEK6/MAP2K6 antibody PA1921. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2017-11-06

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-11-06

Question

Is a blocking peptide available for product anti-MEK6/MAP2K6 antibody (PA1921)?

Verified Customer

Verified customer

Asked: 2017-05-17

Answer

We do provide the blocking peptide for product anti-MEK6/MAP2K6 antibody (PA1921). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2017-05-17

Question

Does anti-MEK6/MAP2K6 antibody PA1921 work for WB with cervix carcinoma?

A. Carter

Verified customer

Asked: 2015-12-04

Answer

According to the expression profile of cervix carcinoma, MAP2K6 is highly expressed in cervix carcinoma. So, it is likely that anti-MEK6/MAP2K6 antibody PA1921 will work for WB with cervix carcinoma.

Boster Scientific Support

Answered: 2015-12-04

Question

We are currently using anti-MEK6/MAP2K6 antibody PA1921 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on pig tissues as well?

J. Williams

Verified customer

Asked: 2015-06-05

Answer

The anti-MEK6/MAP2K6 antibody (PA1921) has not been tested for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2015-06-05

Question

Do you have a BSA free version of anti-MEK6/MAP2K6 antibody PA1921 available?

S. Moore

Verified customer

Asked: 2013-07-31

Answer

We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-MEK6/MAP2K6 antibody PA1921 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2013-07-31

Question

Can you help my question with product PA1921, anti-MEK6/MAP2K6 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

A. Mangal

Verified customer

Asked: 2013-04-01

Answer

We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PA1921 anti-MEK6/MAP2K6 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2013-04-01

Order DetailsPrice
PA1921

100μg

$370
PA1921-10ug

10μg sample (liquid)

$99
PA1921-Biotin

100 μg Biotin conjugated

$570
PA1921-Cy3

100 μg Cy3 conjugated

$570
PA1921-Dylight488

100 μg Dylight488 conjugated

$570
PA1921-Dylight550

100 μg Dylight550 conjugated

$570
PA1921-Dylight594

100 μg Dylight594 conjugated

$570
PA1921-FITC

100 μg FITC conjugated

$570
PA1921-HRP

100 μg HRP conjugated

$570
PA1921-APC

100 μg APC conjugated

$670
PA1921-PE

100 μg PE conjugated

$670
PA1921-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA1921
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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