Anti-MEKK2/MAP3K2 Antibody Picoband™

MEKK2 antibody

Boster Bio Anti-MEKK2/MAP3K2 Antibody Picoband™ catalog # A02354-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat.

Product Info Summary

SKU: A02354-1
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: Flow Cytometry, IF, ICC, WB

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Product Name

Anti-MEKK2/MAP3K2 Antibody Picoband™

View all MEKK2 Antibodies

SKU/Catalog Number

A02354-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MEKK2/MAP3K2 Antibody Picoband™ catalog # A02354-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MEKK2/MAP3K2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02354-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human MEKK2/MAP3K2 recombinant protein (Position: M1-Q364).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A02354-1 is reactive to MAP3K2 in Human, Rat

Applications

A02354-1 is guaranteed for Flow Cytometry, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

78 kDa

Calculated molecular weight

69.741kDa

Background of MEKK2

MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For MAP3K2 (Source: Uniprot.org, NCBI)

Gene Name

MAP3K2

Full Name

Mitogen-activated protein kinase kinase kinase 2

Weight

69.741kDa

Superfamily

protein kinase superfamily

Alternative Names

EC 2.7.11.25; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen-activated protein kinase kinase kinase 2 MAP3K2 MEKK2, MEKK2B mitogen-activated protein kinase kinase kinase 2 mitogen-activated protein kinase kinase kinase 2|MAP/ERK kinase kinase 2|MAPK/ERK kinase kinase 2|MEK kinase 2|MEKK 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAP3K2, check out the MAP3K2 Infographic

MAP3K2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAP3K2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02354-1

100μg

$370
A02354-1-10ug

10μg sample (liquid)

$99
A02354-1-Biotin

100 μg Biotin conjugated

$570
A02354-1-Cy3

100 μg Cy3 conjugated

$570
A02354-1-Dylight488

100 μg Dylight488 conjugated

$570
A02354-1-Dylight550

100 μg Dylight550 conjugated

$570
A02354-1-Dylight594

100 μg Dylight594 conjugated

$570
A02354-1-FITC

100 μg FITC conjugated

$570
A02354-1-HRP

100 μg HRP conjugated

$570
A02354-1-APC

100 μg APC conjugated

$670
A02354-1-PE

100 μg PE conjugated

$670
A02354-1-carrier-free

Carrier Free

$370

More conjugates/formats

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A02354-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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