Product Info Summary
SKU: | A06081 |
---|---|
Size: | 100 ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Melanophilin MLPH Antibody
View all Melanophilin Antibodies
SKU/Catalog Number
A06081
Size
100 ul
Form
Liquid
Description
Boster Bio Anti-Melanophilin MLPH Antibody catalog # A06081. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Melanophilin MLPH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06081)
Host
Rabbit
Contents
Rabbit IgG, 1 mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant full length Human MLPH.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06081 is reactive to MLPH in Human, Mouse, Rat
Applications
A06081 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
65.949kDa
Background of Melanophilin
Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
Ohnishi T., Mol. Cell 12:1187-1200(2003).
Nagase T., DNA Res. 3:321-329(1996).
Nakajima D., DNA Res. 9:99-106(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts of various cell lines, using MLPH antibody at 1:1000 dilution.
Protein Target Info & Infographic
Gene/Protein Information For MLPH (Source: Uniprot.org, NCBI)
Gene Name
MLPH
Full Name
Melanophilin
Weight
65.949kDa
Alternative Names
exophilin-3; l(1)-3Rk; l1Rk3; ln; melanophilin; MGC2771; MGC59733; SLAC2A; Slac-2a; SLAC2-A; Slp homolog lacking C2 domains a; Synaptotagmin-like protein 2a MLPH SLAC2-A melanophilin melanophilin|exophilin-3|slp homolog lacking C2 domains a|synaptotagmin-like protein 2a
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MLPH, check out the MLPH Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MLPH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Melanophilin MLPH Antibody (A06081)
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No publications found for A06081
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