Product Info Summary
SKU: | A01758 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-METTL3 Antibody
View all Methyltransferase like 3 Antibodies
SKU/Catalog Number
A01758
Size
100ul
Form
Liquid
Description
Boster Bio Anti-METTL3 Antibody catalog # A01758. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-METTL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01758)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human COL4A3
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01758 is reactive to Mettl3 in Human, Mouse, Rat
Applications
A01758 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
64.616kDa
Background of Methyltransferase like 3
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Lixin Zhu, Am J Physiol Cell Physiol, Jun 2005; 288: C1242 - C1254.
H.J. Spence, Hum. Mol. Genet., Aug 2004; 13: 1657 - 1668.
Vera L¨²cia Bonilha, J. Cell Biol., Dec 1999; 147: 1533.
M Berryman, J. Cell Biol., Dec 1995; 131: 1231.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Mettl3 (Source: Uniprot.org, NCBI)
Gene Name
Mettl3
Full Name
N6-adenosine-methyltransferase subunit METTL3
Weight
64.616kDa
Superfamily
MT-A70-like family
Alternative Names
adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; EC 2.1.1.62; IME4; M6A; methyltransferase like 3; Methyltransferase-like protein 3; MGC4336; mRNA m(6)A methyltransferase; MTA70; MT-A70; N6-adenosine-methyltransferase 70 kDa subunit; Spo8 Mettl3|2310024F18Rik, M6, M6A, S, Spo8|methyltransferase like 3|N6-adenosine-methyltransferase subunit METTL3|MT-A70|N6-adenosine-methyltransferase 70 kDa subunit|m6a methyltransferase|methyltransferase-like protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Mettl3, check out the Mettl3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Mettl3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-METTL3 Antibody (A01758)
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No publications found for A01758
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Customer Reviews
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