Anti-MettL7B Antibody

Product Name

Anti-MettL7B Antibody

View all METTL7B Antibodies

SKU/Catalog Number

A17310

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-MettL7B Antibody (Catalog # A17310). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

MettL7B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-MettL7B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A17310)

Host

Rabbit

Contents

MettL7B Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

MettL7B antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MettL7B. The immunogen is located within the last 50 amino acids of MettL7B.

Cross-reactivity

This MettL7B antibody is predicted to not cross-react with MettL7A.

Reactive Species

A17310 is reactive to METTL7B in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

27.8 kDa

Background of METTL7B

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A17310 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

MettL7B antibody can be used for detection of Mettl7B by Western blot at 2 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information METTL7B

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