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Product Info Summary
|Reactive Species:||Human, Rat|
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Boster Bio Anti-MFSD2B Antibody (Catalog # A17784). Tested in ELISA, WB applications. This antibody reacts with Human, Rat.
Storage & Handling
MFSD2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MFSD2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A17784)
MFSD2B Antibody is supplied in PBS containing 0.02% sodium azide.
MFSD2B antibody was raised against a 15 amino acid synthetic peptide near the center of human MFSD2B. The immunogen is located within amino acids 240 - 290 of MFSD2B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
A17784 is reactive to MFSD2B in Human, Rat
A17784 is guaranteed for ELISA, WB Boster Guarantee
Background of MFSD2B
Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
MFSD2B antibody can be used for detection of MFSD2B by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Validation Images & Assay Conditions
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Western blot analysis of MFSD2B in rat lung tissue lysate with MFSD2B antibody at (A) 1 and (B) 2 μg/mL.
Gene/Protein Information For MFSD2B (Source: Uniprot.org, NCBI)
Major facilitator superfamily domain-containing protein 2B
major facilitator superfamily
MFSD2B major facilitator superfamily domain containing 2B MFSD2B SLC59A2 major facilitator superfamily domain containing 2B major facilitator superfamily domain-containing protein 2B|S1P transporter|hMfsd2b|sphingosine 1-phosphate transporter*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on MFSD2B, check out the MFSD2B Infographic
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In this infographic, you will see the following information for MFSD2B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
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