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- Table of Contents
MFN1 antibody (A02172) performs well in ELISA, ICC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
Filter:
Immunocytochemistry of MFN1 in A431 cells with MFN1 antibody at 5 μg/mL.
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Anti-Mitofusin-1 MFN1 Antibody
MFN1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, ICC, WB |
Recommend Dilution
Application
Dilution
Species
MFN1 antibody can be used for detection of MFN1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Mitofusin-1 MFN1 Antibody
View all MFN1 Antibodies
View all MFN1 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
MFN1 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
MFN1 antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1. The immunogen is located within amino acids 20 - 70 of MFN1.
Cross-Reactivity
MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
84.2 kDa
Background of MFN1
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4).
Cite This Product
Anti-Mitofusin-1 MFN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02172)
Publications
Application:
Species:
Jiao Z,Wu Y,Qu S.Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system.Cell Death Discov.2020 Aug 25;6:78.doi:10.1038/s41420-020-00313-y.PMID:32884840;PMCID:PMC7447795.
Species: Mouse
PMID: 32884840
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Product Promise
We promise Anti-Mitofusin-1 MFN1 Antibody performs excellently in relevant applications for ELISA, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
A02172
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 3, 2026