Anti-Mitofusin 1 MFN1 Antibody Picoband™ (monoclonal, 3H3)

Mitofusin 1 antibody

Boster Bio Anti-Mitofusin 1 MFN1 Antibody Picoband™ (monoclonal, 3H3) catalog # M02172-1. Tested in IF, ICC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M02172-1
Size: 100 μg/vial
Reactive Species: Human
Host: Mouse
Application: IF, ICC, WB

Product Name

Anti-Mitofusin 1 MFN1 Antibody Picoband™ (monoclonal, 3H3)

View all Mitofusin 1 Antibodies

SKU/Catalog Number

M02172-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Mitofusin 1 MFN1 Antibody Picoband™ (monoclonal, 3H3) catalog # M02172-1. Tested in IF, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mitofusin 1 MFN1 Antibody Picoband™ (monoclonal, 3H3) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02172-1)

Host

Mouse

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Monoclonal

Clone Number

3H3

Isotype

Mouse IgG2b

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1, different from the related mouse and rat sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

M02172-1 is reactive to MFN1 in Human

Applications

M02172-1 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

84 kDa

Calculated molecular weight

84.16kDa

Background of Mitofusin 1

Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80­90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN­2, and to undergo ubiquitination by MARCH5. MFN­1 has two key domains. One is a coiled­coil region that mediates MFN­1: MFN­1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For MFN1 (Source: Uniprot.org, NCBI)

Gene Name

MFN1

Full Name

Mitofusin-1

Weight

84.16kDa

Superfamily

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

DKFZp762F247; EC 3.6.5; EC 3.6.5.-; FLJ20693; Fzo homolog; hfzo1; hfzo2; MFN1; MGC41806; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO-2; Mitofusin 1; mitofusin-1; putative transmembrane GTPase; Transmembrane GTPase MFN1 MFN1 hfzo1, hfzo2 mitofusin 1 mitofusin-1|fzo homolog|mitochondrial transmembrane GTPase FZO-2|mitochondrial transmembrane GTPase Fzo-1|putative transmembrane GTPase|transmembrane GTPase MFN1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MFN1, check out the MFN1 Infographic

MFN1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MFN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M02172-1

100μg

$370
M02172-1-10ug

10μg sample (liquid)

$99
M02172-1-Biotin

100 μg Biotin conjugated

$570
M02172-1-Cy3

100 μg Cy3 conjugated

$570
M02172-1-Dylight488

100 μg Dylight488 conjugated

$570
M02172-1-Dylight550

100 μg Dylight550 conjugated

$570
M02172-1-Dylight594

100 μg Dylight594 conjugated

$570
M02172-1-FITC

100 μg FITC conjugated

$570
M02172-1-HRP

100 μg HRP conjugated

$570
M02172-1-APC

100 μg APC conjugated

$670
M02172-1-PE

100 μg PE conjugated

$670
M02172-1-carrier-free

Carrier Free

$370

More conjugates/formats

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M02172-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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