Anti-MMACHC Antibody

MMACHC antibody

Boster Bio Anti-MMACHC Antibody catalog # A03398. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A03398
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

Product Name

Anti-MMACHC Antibody

View all MMACHC Antibodies

SKU/Catalog Number

A03398

Size

100ul

Form

Liquid

Description

Boster Bio Anti-MMACHC Antibody catalog # A03398. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MMACHC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03398)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CSPG4 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03398 is reactive to MMACHC in Human, Mouse, Rat

Applications

A03398 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

31.728kDa

Background of MMACHC

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Qian Wang, J. Virol., Jan 2004; 78: 821 - 833. RD Paladini,
RD Paladini, J. Cell Biol., Feb 1996; 132: 381.
M.K. Shamsher, Hum. Mol. Genet., Oct 1995; 4: 1875 - 1881.
Ying-Nai Wang, Mol. Pharmacol., Jan 2006; 69: 85 - 98.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For MMACHC (Source: Uniprot.org, NCBI)

Gene Name

MMACHC

Full Name

Methylmalonic aciduria and homocystinuria type C protein

Weight

31.728kDa

Superfamily

MMACHC family

Alternative Names

cblC; DKFZP564I122; FLJ25671; methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; RP11-291L19.3 MMACHC cblC metabolism of cobalamin associated C cyanocobalamin reductase / alkylcobalamin dealkylase|alkylcobalamin:glutathione S-alkyltransferase|cyanocobalamin reductase (cyanide-eliminating)|methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria|methylmalonic aciduria and homocystinuria type C protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MMACHC, check out the MMACHC Infographic

MMACHC infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MMACHC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03398-100ul

100ul

$405

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