Product Info Summary
SKU: | PA1053 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Morg1/WDR83 Antibody
SKU/Catalog Number
PA1053
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Morg1/WDR83 Antibody catalog # PA1053. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Morg1/WDR83 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1053)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Morg1, identical to the related mouse and rat sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1053 is reactive to Wdr83 in Human, Mouse, Rat
Applications
PA1053 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
12 kDa
Calculated molecular weight
34.444kDa
Background of Morg1
MORG1 (mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase (ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate, or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-Morg1 antibody, PA1053, Western blotting
WB: Rat Brain Tissue Lysate
Click image to see more details
Anti-Morg1 antibody, PA1053, IHC(P)
IHC(P): Rat Lung Tissue
Protein Target Info & Infographic
Gene/Protein Information For Wdr83 (Source: Uniprot.org, NCBI)
Gene Name
Wdr83
Full Name
WD repeat domain-containing protein 83
Weight
34.444kDa
Superfamily
WD repeat MORG1 family
Alternative Names
MAPK organizer 1; MGC4238; MORG1Mitogen-activated protein kinase organizer 1; WD repeat domain 83; WD repeat domain-containing protein 83 Wdr83|1500041N16Rik, Mor, Morg1|WD repeat domain containing 83|WD repeat domain-containing protein 83|MAPK cascade scaffold protein|MAPK organizer 1|mitogen-activated protein kinase organizer 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Wdr83, check out the Wdr83 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Wdr83: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Morg1/WDR83 Antibody (PA1053)
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No publications found for PA1053
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-Morg1/WDR83 Antibody
Question
Will anti-Morg1/WDR83 antibody PA1053 work for WB with cerebellum?
Verified Customer
Verified customer
Asked: 2018-08-29
Answer
According to the expression profile of cerebellum, WDR83 is highly expressed in cerebellum. So, it is likely that anti-Morg1/WDR83 antibody PA1053 will work for WB with cerebellum.
Boster Scientific Support
Answered: 2018-08-29
Question
We are currently using anti-Morg1/WDR83 antibody PA1053 for rat tissue, and we are satisfied with the IHC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on dog tissues as well?
R. Anderson
Verified customer
Asked: 2013-09-30
Answer
The anti-Morg1/WDR83 antibody (PA1053) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2013-09-30
Question
Do you have a BSA free version of anti-Morg1/WDR83 antibody PA1053 available?
E. Parker
Verified customer
Asked: 2013-09-27
Answer
We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Morg1/WDR83 antibody PA1053 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2013-09-27