Anti-(Mouse) Dnmt1 Antibody (Center)

DNMT1 antibody

Boster Bio Anti-(Mouse) Dnmt1 Antibody (Center) (Catalog # M00172-2). Tested in WB, IHC-P, IF application(s). This antibody reacts with Human, Mouse.

Product Info Summary

SKU: M00172-2
Size: 80 µl
Reactive Species: Human, Mouse
Host: Rabbit
Application: IF, IHC-P, WB

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Product Name

Anti-(Mouse) Dnmt1 Antibody (Center)

View all DNMT1 Antibodies

SKU/Catalog Number

M00172-2

Size

80 µl

Description

Boster Bio Anti-(Mouse) Dnmt1 Antibody (Center) (Catalog # M00172-2). Tested in WB, IHC-P, IF application(s). This antibody reacts with Human, Mouse.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-(Mouse) Dnmt1 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00172-2)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Clone Number

1504CT774.14.55

Isotype

Rabbit IgG

Immunogen

This MouseDnmt1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 881-914 amino acids from the Central region of mouse Dnmt1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00172-2 is reactive to DNMT1 in Human, Mouse

Applications

M00172-2 is guaranteed for IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

183.165kDa

Background of DNMT1

Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IF: 1:50
WB: 1:1000
IHC-P: 1:25

Validation Images & Assay Conditions

Gene/Protein Information For DNMT1 (Source: Uniprot.org, NCBI)

Gene Name

DNMT1

Full Name

DNA (cytosine-5)-methyltransferase 1

Weight

183.165kDa

Superfamily

class I-like SAM-binding methyltransferase superfamily

Alternative Names

AIM; CXXC9; CXXC9CXXC finger protein 9; CXXC-type zinc finger protein 9; DNA (cytosine-5-)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA MTase HsaI; DNMT; DNMT1; EC 2.1.1.37; FLJ16293; m.HsaI; MCMT; MCMTMGC104992 DNMT1 ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI DNA methyltransferase 1 DNA (cytosine-5)-methyltransferase 1|CXXC-type zinc finger protein 9|DNA (cytosine-5-)-methyltransferase 1|DNA MTase HsaI|DNA methyltransferase HsaI

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DNMT1, check out the DNMT1 Infographic

DNMT1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DNMT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M00172-2-80ul

80 µl

$298
M00172-2-400ul

400 µl

$460

Free Secondary Antibody

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M00172-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$298.00

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