Anti-MPYS TMEM173 Antibody

STING1 antibody

Boster Bio Anti-MPYS TMEM173 Antibody (Catalog # A01871-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A01871-1
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, ICC, WB

Customers Who Bought This Also Bought

Product Name

Anti-MPYS TMEM173 Antibody

View all STING1 Antibodies

SKU/Catalog Number

A01871-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-MPYS TMEM173 Antibody (Catalog # A01871-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

MPYS antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-MPYS TMEM173 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01871-1)

Host

Rabbit

Contents

MPYS Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

Anti-MPYS antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human MPYS. The immunogen is located within amino acids 260-310 of MPYS.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

FOXG1 antibody is human, mouse and rat reactive.

Reactive Species

A01871-1 is reactive to STING1 in Human, Mouse

Applications

A01871-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

42.193kDa

Background of STING1

MPYS is a recently identified plasma membrane tetraspanner that is associated with major histocompatibility complex class II (MHC-II) and mediates its transduction of apoptotic signals. It has also been found to be associated with VISA, a mitochondrial protein that acts as an adaptor in virus-triggered signaling. MPYS also interacts with IRF3 and recruits the kinase TBK1 to the VISA-associated complex, acting as a critical mediator of virus-triggered IRF3 activation and interferon (IFN) expression. It is thought that the binding of nucleic acid to the innate immune protein RIG-I causes complex formation between RIG-I, VISA, and MPYS. This complex then recruits TBK1 to phosphorylate IRF3 which then directly activates IFN transcription. At least three isoforms of MPYS are known to exist.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1-2 μg/mL; ICC: 5 μg/mL; IF: 20 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunocytochemistry and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For STING1 (Source: Uniprot.org, NCBI)

Gene Name

STING1

Full Name

Stimulator of interferon genes protein

Weight

42.193kDa

Superfamily

STING family

Alternative Names

Stimulator of interferon genes protein STING1 ERIS, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173, hMITA, hSTING stimulator of interferon response cGAMP interactor 1 stimulator of interferon genes protein|N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner|endoplasmic reticulum IFN stimulator|endoplasmic reticulum interferon stimulator|mitochondrial mediator of IRF3 activation|stimulator of interferon protein|transmembrane protein 173

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on STING1, check out the STING1 Infographic

STING1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for STING1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for A01871-1

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-MPYS TMEM173 Antibody?

Submit a review and receive an Amazon gift card.

  • $30 for a review with an image

Be the first to review Anti-MPYS TMEM173 Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

0 Customer Q&As for Anti-MPYS TMEM173 Antibody

Order DetailsPrice
A01871-1-0.1 mg

0.1 mg

$449

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
In stock
Order Product
A01871-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.