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We validate the specificity of these antibodies to Sting1 by testing them on tissues known to express Sting1 positively and negatively. Browse below to find the Sting1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.
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Facts about Stimulator of interferon genes protein.
Acts by recognizing and binding cyclic di-GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced in response to DNA virus from the cytosol: upon binding of c-di-GMP or cGAMP, autoinhibition is relieved and TMEM173/STING can activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and employ a potent antifungal state. May be involved in translocon feature, the translocon maybe being able to influence the induction of type I interferons.
Stimulator of interferon genes protein
Present in spleen and thymus tissue. Also present in dendritic cells (at protein level).