Anti-MVD Antibody Picoband™

MVD antibody

Boster Bio Anti-MVD Antibody Picoband™ catalog # A01631-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: A01631-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-MVD Antibody Picoband™

View all MVD Antibodies

SKU/Catalog Number

A01631-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MVD Antibody Picoband™ catalog # A01631-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MVD Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01631-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MVD, which shares 97.3% amino acid (aa) sequence identity with both mouse and rat MVD.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01631-1 is reactive to MVD in Human, Mouse, Rat

Applications

A01631-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

45 kDa

Calculated molecular weight

43.405kDa

Background of MVD

The enzyme mevalonate pyrophosphate decarboxylase (MVD; EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For MVD (Source: Uniprot.org, NCBI)

Gene Name

MVD

Full Name

Diphosphomevalonate decarboxylase

Weight

43.405kDa

Superfamily

diphosphomevalonate decarboxylase family

Alternative Names

EC 4.1.1.33; FP17780; MDDase; mevalonate (diphospho) decarboxylase; Mevalonate (diphospho)decarboxylase; Mevalonate pyrophosphate decarboxylase; MPDdiphosphomevalonate decarboxylase MVD FP17780, MDDase, MPD, POROK7 mevalonate diphosphate decarboxylase diphosphomevalonate decarboxylase|mevalonate (diphospho) decarboxylase|mevalonate pyrophosphate decarboxylase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MVD, check out the MVD Infographic

MVD infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MVD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A01631-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

antitumor effects of nadroparin combined with radiotherapy in lewis lung cancer models

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4 Customer Q&As for Anti-MVD Antibody Picoband™

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for placenta using anti-MVD antibody A01631-1. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2020-02-10

Answer

I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2020-02-10

Question

I have a question about product A01631-1, anti-MVD antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2020-01-06

Answer

We do not recommend storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free A01631-1 anti-MVD antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2020-01-06

Question

Would A01631-1 anti-MVD antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

C. Jha

Verified customer

Asked: 2015-12-14

Answer

It shows on the product datasheet, A01631-1 anti-MVD antibody as been tested on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2015-12-14

Question

We are currently using anti-MVD antibody A01631-1 for rat tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on zebrafish tissues as well?

M. Banerjee

Verified customer

Asked: 2014-08-22

Answer

The anti-MVD antibody (A01631-1) has not been tested for cross reactivity specifically with zebrafish tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2014-08-22

Order DetailsPrice
A01631-1

100μg

$370
A01631-1-10ug

10μg sample (liquid)

$99
A01631-1-Biotin

100 μg Biotin conjugated

$570
A01631-1-Cy3

100 μg Cy3 conjugated

$570
A01631-1-Dylight488

100 μg Dylight488 conjugated

$570
A01631-1-Dylight550

100 μg Dylight550 conjugated

$570
A01631-1-Dylight594

100 μg Dylight594 conjugated

$570
A01631-1-FITC

100 μg FITC conjugated

$570
A01631-1-HRP

100 μg HRP conjugated

$570
A01631-1-APC

100 μg APC conjugated

$670
A01631-1-PE

100 μg PE conjugated

$670
A01631-1-carrier-free

Carrier Free

$370

More conjugates/formats

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A01631-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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