Anti-NALP5 NLRP5 Antibody

Nlrp5 antibody

Boster Bio Anti-NALP5 NLRP5 Antibody (Catalog # A08138). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A08138
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-NALP5 NLRP5 Antibody

View all Nlrp5 Antibodies

SKU/Catalog Number

A08138

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-NALP5 NLRP5 Antibody (Catalog # A08138). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

NALP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-NALP5 NLRP5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08138)

Host

Rabbit

Contents

NALP5 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5. The immunogen is located within the last 50 amino acids of NALP5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody will not cross-react with JMJD1A or JMJD1C.

Reactive Species

A08138 is reactive to Nlrp5 in Human, Mouse, Rat

Applications

A08138 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

131.318kDa

Background of Nlrp5

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

NALP5 antibody can be used for detection of NALP5 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For Nlrp5 (Source: Uniprot.org, NCBI)

Gene Name

Nlrp5

Full Name

NACHT, LRR and PYD domains-containing protein 5

Weight

131.318kDa

Alternative Names

CLR19.8; MATERMater protein homolog; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; NALP5maternal antigen that embryos require; NLR family, pyrin domain containing 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 5; PAN11; PYPAF8 Nlrp5|Mat, Mater, N, Nalp5, O, Op1, PAN11|NLR family, pyrin domain containing 5|NACHT, LRR and PYD domains-containing protein 5|NACHT, leucine rich repeat and PYD containing 5|maternal antigen that embryos require|ooplasm-specific protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Nlrp5, check out the Nlrp5 Infographic

Nlrp5 infographic

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In this infographic, you will see the following information for Nlrp5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A08138-0.1 mg

0.1 mg

$449

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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