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Product Info Summary
| SKU: | A03636 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-NALP6 NLRP6 Antibody
SKU/Catalog Number
A03636
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NALP6 NLRP6 Antibody (Catalog # A03636). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
NALP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NALP6 NLRP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03636)
Host
Rabbit
Contents
NALP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6. The immunogen is located within amino acids 150 - 200 of NALP6.
Reactive Species
A03636 is reactive to NLRP6 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
98.8 kDa
Background of NLRP6
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-κB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03636 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NALP6 antibody can be used for detection of NALP6 by Western blot at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NALP6 in HeLa, MCF-7 and THP-1 with NALP6 antibody at 2 μg/mL.
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Immunofluorescence of NALP6 in human brain tissue with NALP6 antibody at 20 μg/mL.
Specific Publications For Anti-NALP6 NLRP6 Antibody (A03636)
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