Anti-NCoA-3 Monoclonal Antibody

NCOA3/AIB1 antibody

Boster Bio Anti-NCoA-3 Monoclonal Antibody catalog # M01337. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M01337
Size: 100ul
Reactive Species: Human
Host: Mouse
Application: ELISA, WB

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Product Name

Anti-NCoA-3 Monoclonal Antibody

View all NCOA3/AIB1 Antibodies

SKU/Catalog Number

M01337

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NCoA-3 Monoclonal Antibody catalog # M01337. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NCoA-3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01337)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

2C11B12

Isotype

IgG

Immunogen

Purified recombinant fragment of NCoA-3 (aa1-200) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M01337 is reactive to NCOA3 in Human

Applications

M01337 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

155.293kDa

Background of NCOA3/AIB1

TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:10000

Validation Images & Assay Conditions

Gene/Protein Information For NCOA3 (Source: Uniprot.org, NCBI)

Gene Name

NCOA3

Full Name

Nuclear receptor coactivator 3

Weight

155.293kDa

Superfamily

SRC/p160 nuclear receptor coactivator family

Alternative Names

ACTR; ACTRCBP-interacting protein; AIB1; AIB1AIB-1; Amplified in breast cancer 1 protein; BHLHE42; bHLHe42p/CIP; CAGH16; Class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; nuclear receptor coactivator 3; pCIP ; pCIP; RAC3; RAC-3; RAC3pCIP; Receptor-associated coactivator 3; SRC-1; SRC3; SRC-3; SRC-3EC 2.3.1.48; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC16; TRAM1; TRAM-1TNRC14 NCOA3 ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP nuclear receptor coactivator 3 nuclear receptor coactivator 3|CBP-interacting protein|amplified in breast cancer 1 protein|class E basic helix-loop-helix protein 42|receptor-associated coactivator 3|steroid receptor coactivator protein 3|thyroid hormone receptor activator molecule 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NCOA3, check out the NCOA3 Infographic

NCOA3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NCOA3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01337-100ul

100ul

$380

Free Secondary Antibody

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M01337
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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