Product Info Summary
SKU: | A06774-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, Flow Cytometry, IHC, WB |
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Product info
Product Name
Anti-NDR2 STK38L Antibody
SKU/Catalog Number
A06774-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-NDR2 STK38L Antibody catalog # A06774-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NDR2 STK38L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06774-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NDR2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06774-1 is reactive to STK38L in Human, Mouse, Rat
Applications
A06774-1 is guaranteed for ELISA, Flow Cytometry, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
54.003kDa
Background of STK38L
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204].
Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101].
Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ICC 1:200-1:1000
ELISA 1:5000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-NDR2 STK38L Antibody A06774-1
Western Blot (WB) analysis of mouse cells using NDR2 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For STK38L (Source: Uniprot.org, NCBI)
Gene Name
STK38L
Full Name
Serine/threonine-protein kinase 38-like
Weight
54.003kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11; EC 2.7.11.1; KIAA0965nuclear Dbf2-related 2; NDR2 protein kinase; NDR2serine/threonine-protein kinase 38-like; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38 like STK38L NDR2 serine/threonine kinase 38 like serine/threonine-protein kinase 38-like|NDR2 protein kinase|nuclear Dbf2-related 2|nuclear Dbf2-related kinase 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STK38L, check out the STK38L Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STK38L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NDR2 STK38L Antibody (A06774-1)
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No publications found for A06774-1
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Customer Reviews
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