Anti-Nesprin-2 SYNE2 Antibody

Nesprin 2 antibody

Boster Bio Anti-Nesprin-2 SYNE2 Antibody catalog # A02818. Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A02818
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: IHC

Product Name

Anti-Nesprin-2 SYNE2 Antibody

View all Nesprin 2 Antibodies

SKU/Catalog Number

A02818

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Nesprin-2 SYNE2 Antibody catalog # A02818. Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Nesprin-2 SYNE2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02818)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human SYNE2 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02818 is reactive to SYNE2 in Human, Mouse

Applications

A02818 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

796.442kDa

Background of Nesprin 2

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.

Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-p 1:50-300

Validation Images & Assay Conditions

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Gene/Protein Information For SYNE2 (Source: Uniprot.org, NCBI)

Gene Name

SYNE2

Full Name

Nesprin-2

Weight

796.442kDa

Superfamily

nesprin family

Alternative Names

DKFZP434H2235; DKFZp686E01115; DKFZp686H1931; EDMD5; FLJ46790; KIAA1011FLJ11014; nesprin 2; Nesprin-2; NUAFLJ43727; NUANCEFLJ45710; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE-2; TROPH SYNE2 EDMD5, KASH2, NUA, NUANCE, Nesp2, Nesprin-2, SYNE-2, TROPH spectrin repeat containing nuclear envelope protein 2 nesprin-2|KASH domain-containing protein 2|nesprin 2|nuclear envelope spectrin repeat protein 2|nucleus and actin connecting element protein|polytrophin|spectrin repeat containing, nuclear envelope 2|synaptic nuclear envelope protein 2|synaptic nuclei expressed gene 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SYNE2, check out the SYNE2 Infographic

SYNE2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SYNE2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02818-100ul

100ul

$380

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A02818
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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