Product Info Summary
SKU: | A10259 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Neuroguidin NGDN Antibody
SKU/Catalog Number
A10259
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Neuroguidin NGDN Antibody catalog # A10259. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Neuroguidin NGDN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10259)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human MYLK2 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A10259 is reactive to NGDN in Human, Mouse, Rat
Applications
A10259 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
35.894kDa
Background of NGDN
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
Nagase T., DNA Res. 6:63-70(1999).
Prekeris R., Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Deloukas P., Nature 429:375-381(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Neuroguidin NGDN Antibody A10259
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For NGDN (Source: Uniprot.org, NCBI)
Gene Name
NGDN
Full Name
Neuroguidin
Weight
35.894kDa
Superfamily
SAS10 family
Alternative Names
C14orf120; DKFZP564O092; EIF4E-binding protein; eukaryotic initiation factor 4E and CPEB binding protein; LCP5; lpd-2; neuroguidin; neuroguidin, EIF4E binding protein; NGDchromosome 14 open reading frame 120 NGDN C14orf120, CANu1, LCP5, NGD, lpd-2 neuroguidin neuroguidin|EIF4E-binding protein|centromere accumulated nuclear protein 1|eukaryotic initiation factor 4E and CPEB binding protein|neuroguidin, EIF4E binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NGDN, check out the NGDN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NGDN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Neuroguidin NGDN Antibody (A10259)
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No publications found for A10259
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Customer Reviews
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