Anti-Neuroligin-2 NLGN2 Antibody

Product Name

Anti-Neuroligin-2 NLGN2 Antibody

View all NLGN2 Antibodies

SKU/Catalog Number

A06595

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Neuroligin-2 NLGN2 Antibody (Catalog # A06595). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Neuroligin-2 NLGN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06595)

Host

Rabbit

Contents

NLGN2 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.

Cross-reactivity

NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.

Reactive Species

A06595 is reactive to NLGN2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

90.8 kDa

Background of NLGN2

Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06595 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information NLGN2

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