Anti-NFIC (4E10) monoclonal Antibody

Product Name

Anti-NFIC (4E10) monoclonal Antibody

View all NFIC Antibodies

SKU/Catalog Number

M04154

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NFIC (4E10) monoclonal Antibody catalog # M04154. Tested in WB,ICC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NFIC (4E10) monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04154)

Host

Mouse

Contents

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

1A8H2C12

Isotype

IgG

Immunogen

Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M04154 is reactive to NFIC in Human

Applications

M04154 is guaranteed for ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

55.675kDa

Background of NFIC

Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000
ICC: 1:100-500

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For NFIC (Source: Uniprot.org, NCBI)

Alternative Names

CCAAT-binding transcription factor; CTF5; CTFCCAAT-box-binding transcription factor; MGC20153; NF1-C; NFI; NF-I; NF-I/C; NFI-C; nuclear factor 1 C-type; Nuclear factor 1/C; nuclear factor I/C (CCAAT-binding transcription factor); Nuclear factor I/C; TGGCA-binding protein NFIC CTF, CTF5, NF-I, NFI nuclear factor I C nuclear factor 1 C-type|CCAAT-box-binding transcription factor|NF-I/C|NF1-C|TGGCA-binding protein|nuclear factor I/C (CCAAT-binding transcription factor)

For more info on NFIC, check out the NFIC Infographic

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In this infographic, you will see the following information for NFIC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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