Anti-Niemann Pick C1 Rabbit Monoclonal Antibody

Product Name

Anti-Niemann Pick C1 Rabbit Monoclonal Antibody

View all Niemann-Pick C1 Antibodies

SKU/Catalog Number

M00428-1

Size

100 μl/vial

Form

Liquid

Description

Boster Bio Anti-Niemann Pick C1 Rabbit Monoclonal Antibody catalog # M00428-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Niemann Pick C1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00428-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

18N07

Isotype

IgG

Immunogen

A synthesized peptide derived from human Niemann Pick C1

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00428-1 is reactive to NPC1 in Human, Mouse, Rat

Applications

M00428-1 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

160-180 kDa

Calculated molecular weight

142.167kDa

Background of Niemann-Pick C1

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:100

Validation Images & Assay Conditions

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Western blot analysis of Niemann Pick C1 expression in HepG2 cell lysate.

Gene/Protein Information For NPC1 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ98532; Niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick Type C1; NPC; NPC1; SLC65A1 NPC1 NPC, POGZ, SLC65A1 NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 1|Niemann-Pick C1 protein|truncated Niemann-Pick C1

For more info on NPC1, check out the NPC1 Infographic

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In this infographic, you will see the following information for NPC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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