Click image to see more details
Product Info Summary
| SKU: | A03822 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-NIK MAP3K14 Antibody
View all NIK/MAP3K14 Antibodies
SKU/Catalog Number
A03822
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NIK MAP3K14 Antibody (Catalog # A03822). Tested in ELISA, WB, IF, ICC applications. This antibody reacts with Human.
Storage & Handling
NIK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NIK MAP3K14 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03822)
Host
Rabbit
Contents
NIK Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NIK antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NIK. The immunogen is located within the last 50 amino acids of NIK.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DEPTOR antibody is human, mouse and rat reactive. At least three isoforms of DEPTOR are known to exist; this antibody will detect all three isoforms.
Reactive Species
A03822 is reactive to MAP3K14 in Human
Applications
A03822 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
104.042kDa
Background of NIK/MAP3K14
Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFα, LPS and mitogens. A serine/threonine protein kinase which mediates NF-κB activation by IL-1, TNFα and CD95 was identified recently and designated NIK (for NF-κB inducing kinase). NIK is an activator of IκB kinase alpha and beta (IKKα and IKKβ). Therefore, NIK is a key molecule in the NF-κB signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NIK antibody can be used for detection of NIK by Western blot at 1 - 2 μg/mL.
Antibody validated: Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Immunocytochemistry of NIK in Hek293 cells with NIK antibody at 10 μg/mL.
Click image to see more details
Immunofluorescence of NIK in Hek293 cells with NIK antibody at 20 μg/mL.
Green: NIK Antibody (A03822)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For MAP3K14 (Source: Uniprot.org, NCBI)
Gene Name
MAP3K14
Full Name
Mitogen-activated protein kinase kinase kinase 14
Weight
104.042kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.11.25; FTDCR1B; HS; HSNIK; HSNIKserine/threonine protein-kinase; MAP3K14; mitogen-activated protein kinase kinase kinase 14; NIK; NIKNF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK MAP3K14 FTDCR1B, HS, HSNIK, NIK mitogen-activated protein kinase kinase kinase 14 mitogen-activated protein kinase kinase kinase 14|NF-kappa-beta-inducing kinase|serine/threonine-protein kinase NIK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAP3K14, check out the MAP3K14 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAP3K14: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NIK MAP3K14 Antibody (A03822)
Hello CJ!
No publications found for A03822
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-NIK MAP3K14 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-NIK MAP3K14 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
