Anti-NMDAR2C/GRIN2C Antibody Picoband™

NMDAR2C antibody

Boster Bio Anti-NMDAR2C/GRIN2C Antibody Picoband™ catalog # PB9374. Tested in WB applications. This antibody reacts with Human, Rat.

Product Info Summary

SKU: PB9374
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: WB

Product Name

Anti-NMDAR2C/GRIN2C Antibody Picoband™

View all NMDAR2C Antibodies

SKU/Catalog Number

PB9374

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-NMDAR2C/GRIN2C Antibody Picoband™ catalog # PB9374. Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NMDAR2C/GRIN2C Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9374)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

PB9374 is reactive to GRIN2C in Human, Rat

Applications

PB9374 is guaranteed for WB Boster Guarantee

Background of NMDAR2C

NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Rat, Human

Validation Images & Assay Conditions

Gene/Protein Information For GRIN2C (Source: Uniprot.org, NCBI)

Uniprot ID

Q14957

Gene ID

2905

Gene Name

GRIN2C

Full Name

Glutamate receptor ionotropic, NMDA 2C

Weight

134.209kDa

Superfamily

glutamate-gated ion channel (TC 1.A.10.1) family

Alternative Names

glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; GRIN2C; NMDA R, NR2C Subunit; NMDAR2C; NMDAR2CNR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2C GRIN2C GluN2C, NMDAR2C, NR2C glutamate ionotropic receptor NMDA type subunit 2C glutamate receptor ionotropic, NMDA 2C|N-methyl D-aspartate receptor subtype 2C|N-methyl-D-aspartate receptor subunit 2C|glutamate [NMDA] receptor subunit epsilon-3|glutamate receptor, ionotropic, N-methyl D-aspartate 2C

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GRIN2C, check out the GRIN2C Infographic

GRIN2C infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GRIN2C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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1 Customer Q&As for Anti-NMDAR2C/GRIN2C Antibody Picoband™

Question

We are currently using anti-NMDAR2C/GRIN2C antibody PB9374 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2020-01-16

Answer

The anti-NMDAR2C/GRIN2C antibody (PB9374) has not been validated for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-01-16

Size

Conjugation

Total: $315

SKU:PB9374

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PB9374
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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