Anti-NNT-1 CLCF1 Antibody

Product Name

Anti-NNT-1 CLCF1 Antibody

View all CLC Antibodies

SKU/Catalog Number

A08886

Size

100μl

Form

Liquid

Description

Boster Bio Anti-NNT-1 CLCF1 Antibody catalog # A08886. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NNT-1 CLCF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08886)

Host

Rabbit

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Clone Number

3D5B1

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 171-220.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A08886 is reactive to CLCF1 in Human, Mouse, Rat

Applications

A08886 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

25.176kDa

Background of CLC

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-P, 1:50-300

Validation Images & Assay Conditions

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Gene/Protein Information For CLCF1 (Source: Uniprot.org, NCBI)

Alternative Names

B-cell stimulating factor 3; B-cell stimulatory factor 3; BSF-3; BSF3BSF-3; cardiotrophin-like cytokine factor 1; CISS2; CLC; CLCF1; CLCNNT-1; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; NNT-1; NNT1B-cell-stimulating factor 3; Novel neurotrophin-1; NR6 CLCF1 BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 cardiotrophin like cytokine factor 1 cardiotrophin-like cytokine factor 1|B-cell stimulatory factor 3|B-cell-stimulating factor 3|CRLF1 associated cytokine-like factor 1|neurotrophin-1/B-cell stimulating factor-3|novel neurotrophin-1

For more info on CLCF1, check out the CLCF1 Infographic

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In this infographic, you will see the following information for CLCF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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