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Product Info Summary
| SKU: | A06014 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-NOSTRIN Antibody
SKU/Catalog Number
A06014
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NOSTRIN Antibody (Catalog # A06014). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
NOSTRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-NOSTRIN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06014)
Host
Rabbit
Contents
NOSTRIN antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN. The immunogen is located within amino acids 430 - 480 of NOSTRIN.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.
Reactive Species
A06014 is reactive to NOSTRIN in Human, Mouse, Rat
Applications
A06014 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
57.66kDa
Background of NOSTRIN
NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NOSTRIN antibody can be used for detection of NOSTRIN by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NOSTRIN in SW480 cell lysate with NOSTRIN antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 5 μg/ml.
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Immunofluorescence of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For NOSTRIN (Source: Uniprot.org, NCBI)
Gene Name
NOSTRIN
Full Name
Nostrin
Weight
57.66kDa
Alternative Names
BM247 homolog; DaIP2; endothelial nitric oxide synthase traffic inducer; ENOS traffic inducer; eNOS-trafficking inducer; Nitric oxide synthase traffic inducer; nitric oxide synthase traffickerMGC20702; nitric oxide synthase trafficking; nostrin; ortholog of mouse disabled 2 interacting proein 2 NOSTRIN DaIP2 nitric oxide synthase trafficking nostrin|BM247 homolog|ENOS traffic inducer|eNOS-trafficking inducer|endothelial nitric oxide synthase traffic inducer|nitric oxide synthase traffic inducer|nitric oxide synthase trafficker|ortholog of mouse disabled 2 interacting proein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NOSTRIN, check out the NOSTRIN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NOSTRIN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NOSTRIN Antibody (A06014)
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No publications found for A06014
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