Click image to see more details
Product Info Summary
| SKU: | A04123-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-OASL Antibody (C-term)
SKU/Catalog Number
A04123-1
Size
80 µl
Description
Boster Bio Anti-OASL Antibody (C-term) (Catalog # A04123-1). Tested in WB, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-OASL Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04123-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This OASL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human OASL.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04123-1 is reactive to OASL in Human
Applications
A04123-1 is guaranteed for IHC-P, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
59.226kDa
Background of OASL
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
IHC-P: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
The anti-OASL C-term Antibody is used in Western blot to detect OASL in HL60 lysate.
Click image to see more details
Western blot analysis of lysates from HT-29, PC-3, U-87 MG cell line and human testis tissue lysate(from left to right), using OASL Antibody T499. A04123-1 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
Click image to see more details
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Protein Target Info & Infographic
Gene/Protein Information For OASL (Source: Uniprot.org, NCBI)
Gene Name
OASL
Full Name
2'-5'-oligoadenylate synthase-like protein
Weight
59.226kDa
Superfamily
2-5A synthase family
Alternative Names
2'-5'-oligoadenylate synthetase-like; p59 OASL; p59OASL59 kDa 2'-5'-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14,59 kDa 2'-5'-oligoadenylate synthetase-like protein; TRIP-14; TRIP14TR-interacting protein 14 OASL OASL1d, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL, OASL 2-5-oligoadenylate synthetase like 2-5-oligoadenylate synthase-like protein|2-5-OAS-RP|2-5-OAS-related protein|59 kDa 2-5-oligoadenylate synthase-like protein|59 kDa 2-5-oligoadenylate synthetase-like protein|TR-interacting protein 14|thyroid receptor-interacting protein 14
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on OASL, check out the OASL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for OASL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-OASL Antibody (C-term) (A04123-1)
Hello CJ!
No publications found for A04123-1
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-OASL Antibody (C-term)?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-OASL Antibody (C-term)
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
