OASL Antibodies

AND OASL ELISA kits, OASL Proteins

Many biological assays use antibodies to detect OASL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OASL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OASL antibodies...

We validate the specificity of these antibodies to OASL by testing them on tissues known to express OASL positively and negatively. Browse below to find the OASL antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for OASL? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the OASL Western Blot Guide

Designing an IHC experiment for OASL? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the OASL IHC Guide

OASL Infographic by Boster Bio

All OASL Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

OASL (NM_003733) Human Over-expression Lysate

Human

$960
Cat # LS008638
20 µg, 100 µg

Anti-OASL Antibody

Western blot analysis of OASL in mouse bladder tissue lysate with OASL antibody at 1 μg/ml

Immunocytochemistry of OASL1 in HepG2 cells with OASL1 antibody at 2

Immunofluorescence of OASL1 in HepG2 cells with OASL1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, ICC, WB

$481
Cat # A04123
0.1 mg

Anti-OASL Antibody (C-term)

The anti-OASL C-term Antibody is used in Western blot to detect OASL in HL60 lysate

Human

IHC-P, WB

$299
Cat # A04123-1
80 µl

OASL Overview

Facts about 2'-5'-oligoadenylate synthase-like protein.

OASL 3D structure. Source: alphafold

2'-5'-oligoadenylate synthase-like protein (OASL)

Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) through another antiviral pathway independent of RNase L.

Gene Information

Human
Gene Name:	OASL
Uniprot:	Q15646
Entrez:	8638

Family

Belongs to:

2-5A synthase family

Alternative Names

2'-5'-oligoadenylate synthetase-like; p59 OASL; p59OASL59 kDa 2'-5'-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14,59 kDa 2'-5'-oligoadenylate synthetase-like protein; TRIP-14; TRIP14TR-interacting protein 14

Molecular Weight

Mass (kDA):
59.226 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (121018882..121039242, complement)

Tissue Specificity

Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.

Subcellular Localizations

[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.

Diseases

Virus Diseases
Hepatitis
Hepatitis C
Lupus Erythematosus, Systemic
Hepatitis C, Chronic
Infective Disorder
Neoplasms
Influenza
Hepatitis, Chronic
Encephalitis
West Nile Viral Infection
Influenza In Birds

Rheumatism
Malignant Neoplasms
Dengue Fever
Inflammation
Cardiovascular Diseases
Tissue Adhesions
Kidney Diseases

Interacting Proteins

LARP7

Pathways

Cell Adhesion
Immune Response
Cell Growth
Pathogenesis
Gene Conversion
Cell Cycle
Virus-host Interaction
Viral Replication
Spermatogenesis

Defense Response
Secretion
Inflammatory Response

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OASL

References

PMID: 9722630 by Hartmann R., et al. p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family.

PMID: 9826176 by Rebouillat D., et al. Molecular cloning and characterization of two related and interferon- induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase.