Anti-ORM1-like protein 1 ORMDL1 Antibody

Product Name

Anti-ORM1-like protein 1 ORMDL1 Antibody

View all ORMDL1 Antibodies

SKU/Catalog Number

A12278

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ORM1-like protein 1 ORMDL1 Antibody (Catalog # A12278). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ORMDL1 antibody can be stored at 4 °C, stable for one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ORM1-like protein 1 ORMDL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12278)

Host

Rabbit

Contents

ORMDL1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ORMDL1 antibody was raised against a 16 amino acid synthetic peptide of human ORMDL1. The immunogen is located within amino acids 50 - 100 of ORMDL1.

Cross-reactivity

ORMDL1 antibody may cross-react with other ORMDL protein family members.

Reactive Species

A12278 is reactive to ORMDL1 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

17.4 kDa

Background of ORMDL1

The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A12278 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ORMDL1 antibody can be used for detection of ORMDL1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information ORMDL1

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