Anti-Ornithine Decarboxylase-1 (ODC-1) Monoclonal Antibody

Product Name

Anti-Ornithine Decarboxylase-1 (ODC-1) Monoclonal Antibody

View all Ornithine Decarboxylase Antibodies

SKU/Catalog Number

M03138

Size

100ug/vial

Form

Liquid

Description

Boster Bio Anti-Ornithine Decarboxylase-1 (ODC-1) Monoclonal Antibody (Catalog # M03138). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Cite This Product

Anti-Ornithine Decarboxylase-1 (ODC-1) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03138)

Host

Mouse

Contents

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Clonality

Monoclonal

Clone Number

Clone: ODC1/487

Isotype

IgG2a, kappa

Immunogen

Recombinant human ODC-1 protein

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M03138 is reactive to ODC1 in Human, Mouse, Rat

Applications

M03138 is guaranteed for Flow Cytometry, IF, IHC, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

51.148kDa

Background of Ornithine Decarboxylase

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Validation Images & Assay Conditions

Click image to see more details

IF staining of LNCap cells using AF488 labeled Anti-ODC1 Monoclonal Antibody (ODC1/487) (Green). DAPI was used to stain the cell nuclei (blue).

Click image to see more details

Formalin-fixed, paraffin-embedded Rat Pancreas stained with Anti-ODC1 Monoclonal Antibody (ODC1/487)

Click image to see more details

Formalin-fixed, paraffin-embedded Mouse Pancreas stained with Anti-ODC1 Monoclonal Antibody (ODC1/487)

Click image to see more details

Formalin-fixed, paraffin-embedded Mouse Small Intestine stained with Anti-ODC1 Monoclonal Antibody (ODC1/487)

Gene/Protein Information For ODC1 (Source: Uniprot.org, NCBI)

Alternative Names

ODC; ODC1; ODCEC 4.1.1.17; ornithine decarboxylase 1; ornithine decarboxylase ODC1 BABS, NEDBA, NEDBIA, ODC ornithine decarboxylase 1 ornithine decarboxylase

For more info on ODC1, check out the ODC1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ODC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the ODC1 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis