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Product Info Summary
|Reactive Species:||Human, Mouse, Rat|
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Anti-P2X purinoceptor 7 P2RX7 Antibody
Boster Bio Anti-P2X purinoceptor 7 P2RX7 Antibody catalog # PA2129. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-P2X purinoceptor 7 P2RX7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2129)
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
A synthetic peptide corresponding to a sequence at the N-terminus of rat P2RX7 (1-20aa MPACCSWNDVFQYETNKVTR), different from the related mouse sequence by one amino acid, and from the related human sequence by two amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
PA2129 is reactive to P2rx7 in Human, Mouse, Rat
PA2129 is guaranteed for WB Boster Guarantee
Background of P2X7/P2RX7
P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene. The product of this gene belongs to the family of purnoceptors for ATP. P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization. It is a receptor for ATP that acts as a ligand-gated ion channel. This gene is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. It could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Validation Images & Assay Conditions
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Anti-P2RX7 antibody, PA2129, Western blotting
WB: U87 Cell Lysate
Gene/Protein Information For P2rx7 (Source: Uniprot.org, NCBI)
P2X purinoceptor 7
P2X receptor family
ATP receptor; MGC20089; P2RX7; P2X purinoceptor 7; P2X7; P2X7P2X7 receptor; P2X7R; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7 variant A; Purinergic receptor P2rx7|purinergic receptor P2X 7|P2X purinoceptor 7|ATP receptor|P2X purinoceptor 7-like|P2X7 purinoceptor|P2Z receptor|purinergic receptor P2X, ligand-gated ion channel, 7|purinergic receptor P2X7*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on P2rx7, check out the P2rx7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for P2rx7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
No publications found for PA2129
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