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Product Info Summary
| SKU: | A11148 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-Palmdelphin PALMD Antibody
SKU/Catalog Number
A11148
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Palmdelphin PALMD Antibody (Catalog # A11148). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.
Storage & Handling
PALMD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Palmdelphin PALMD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11148)
Host
Rabbit
Contents
PALMD antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PALMD antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PALMD. The immunogen is located within amino acids 460 - 510 of PALMD.
Cross-reactivity
PALMD antibody is human specific. At least two isoforms are known to exist.
Reactive Species
A11148 is reactive to PALMD in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
62.8 kDa
Background of PALMD
Palmdelphin (PALMD) is a member of the paralemmin families that are lipid-anchored proteins having a role in the cell shape control and cell dynamics (1,2). While Paralemmin proteins typically anchor to the cytoplasm through via palmytoylation and prenylation, PALMD is found predominantly in the cytosol (3). PALMD is targeted to the nucleus to induce apoptosis in response to DNA damage (3-5). Abnormal genetic alterations in PALMD are observed in many malignant tumors (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11148 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PALMD antibody can be used for detection of PALMD by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PALMD in human bladder tissue lysate with PALMD antibody at 1 μg/ml.
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Immunohistochemistry of PALMD in human bladder tissue with PALMD antibody at 2.5 μg/mL.
Specific Publications For Anti-Palmdelphin PALMD Antibody (A11148)
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