Anti-Pannexin-1 PANX1 Antibody

Pannexin-1 antibody

Boster Bio Anti-Pannexin-1 PANX1 Antibody (Catalog # A00915). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00915
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, WB

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Product Name

Anti-Pannexin-1 PANX1 Antibody

View all Pannexin-1 Antibodies

SKU/Catalog Number

A00915

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Pannexin-1 PANX1 Antibody (Catalog # A00915). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

PANX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Pannexin-1 PANX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00915)

Host

Rabbit

Contents

PANX1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1. The immunogen is located within amino acids 70 - 120 of PANX1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Two transcript variants encoding different isoforms have been found for this gene.

Reactive Species

A00915 is reactive to PANX1 in Human, Mouse, Rat

Applications

A00915 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

48.05kDa

Background of Pannexin-1

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For PANX1 (Source: Uniprot.org, NCBI)

Gene Name

PANX1

Full Name

Pannexin-1

Weight

48.05kDa

Superfamily

pannexin family

Alternative Names

Innexin; MGC21309; MRS1; MRS1innexin; pannexin 1; Pannexin1; Pannexin-1; PANX1; PX1; UNQ2529 PANX1 MRS1, OOMD7, PX1, UNQ2529 pannexin 1 pannexin-1|innexin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PANX1, check out the PANX1 Infographic

PANX1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PANX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00915-0.1 mg

0.1 mg

$449

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