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Product Info Summary
| SKU: | A01897-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC, WB |
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Product info
Product Name
Anti-PARD3A Antibody
View all PARD3/Par3 Antibodies
SKU/Catalog Number
A01897-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PARD3A Antibody catalog # A01897-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PARD3A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01897-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human PARD3A
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01897-1 is reactive to PARD3 in Human, Mouse, Rat
Applications
A01897-1 is guaranteed for ELISA, IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
151.423kDa
Background of PARD3/Par3
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Joberty G., Nat. Cell Biol. 2:531-539(2000).
Fang C.M., Cell Res. 11:223-229(2001).
Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-PARD3A Antibody A01897-1
Western Blot (WB) analysis of specific cells using PARD3A polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For PARD3 (Source: Uniprot.org, NCBI)
Gene Name
PARD3
Full Name
Partitioning defective 3 homolog
Weight
151.423kDa
Superfamily
PAR3 family
Alternative Names
ASIP; Baz; Bazooka; FLJ21015; par-3 partitioning defective 3 homolog (C. elegans); PAR3; PAR3A; PAR3C.elegans) homolog; PARD3; SE2-5L16; SE2-5LT1; SE2-5T2 PARD3 ASIP, Baz, PAR3, PAR3alpha, PARD-3A, PPP1R118, SE2-5L16, SE2-5LT1, SE2-5T2, PARD3 par-3 family cell polarity regulator partitioning defective 3 homolog|CTCL tumor antigen se2-5|PAR3-alpha|atypical PKC isotype-specific interacting protein|bazooka|par-3 family cell polarity regulator alpha|par-3 partitioning defective 3 homolog|protein phosphatase 1, regulatory subunit 118
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PARD3, check out the PARD3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PARD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PARD3A Antibody (A01897-1)
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No publications found for A01897-1
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Customer Reviews
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