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Product Info Summary
| SKU: | A02572S885 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-Lfc (S885) ARHGEF2 Antibody
SKU/Catalog Number
A02572S885
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-Lfc (S885) ARHGEF2 Antibody catalog # A02572S885. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-Lfc (S885) ARHGEF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02572S885)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Lfc around the phosphorylation site of S885.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02572S885 is reactive to ARHGEF2 in Human, Mouse, Rat
Applications
A02572S885 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
111.543kDa
Background of GEF-H1
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.
Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
Grimwood J., Nature 428:529-535(2004).
Tatematsu K., Genes Cells 5:677-688(2000).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
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Figure 1. Immunohistochemistry validation of ARHGEF2 using Anti-Phospho-Lfc (S885) ARHGEF2 Antibody (A02572S885).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°CProtein Target Info & Infographic
Gene/Protein Information For ARHGEF2 (Source: Uniprot.org, NCBI)
Gene Name
ARHGEF2
Full Name
Rho guanine nucleotide exchange factor 2
Weight
111.543kDa
Alternative Names
GEF; GEFH1; GEF-H1DKFZp547P1516; Guanine nucleotide exchange factor H1; KIAA0651DKFZp547L106; LFP40FLJ45440; Microtubule-regulated Rho-GEF; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2 ARHGEF2 GEF, GEF-H1, GEFH1, LFP40, Lfc, NEDMHM, P40 Rho/Rac guanine nucleotide exchange factor 2 rho guanine nucleotide exchange factor 2|Rho/Rac guanine nucleotide exchange factor (GEF) 2|guanine nucleotide exchange factor H1|microtubule-regulated Rho-GEF|proliferating cell nucleolar antigen p40
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARHGEF2, check out the ARHGEF2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARHGEF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Lfc (S885) ARHGEF2 Antibody (A02572S885)
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No publications found for A02572S885
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