Product Info Summary
SKU: | A00800S330 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody
View all Presenilin-2 Antibodies
SKU/Catalog Number
A00800S330
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody catalog # A00800S330. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00800S330)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Presenilin 2 around the phosphorylation site of S330.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00800S330 is reactive to PSEN2 in Human, Mouse, Rat
Applications
A00800S330 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
50.14kDa
Background of Presenilin-2
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
Arja Lamberg, J. Biol. Chem., May 1996; 271: 11988.
GW Conrad, J. Cell Biol., Mar 1980; 84: 501.
DR Keene, J. Cell Biol., Nov 1987; 105: 2393.
HM Wang, J. Histochem. Cytochem., Nov 1980; 28: 1215.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of PSEN2 using Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody (A00800S330).
Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°CClick image to see more details
Figure 2. Immunohistochemistry validation of PSEN2 using Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody (A00800S330).
Immunohistochemical analysis of paraffin-embedded Human colon cancer. Antibody was diluted at 1:100 (4°CClick image to see more details
Figure 3. Immunohistochemistry validation of PSEN2 using Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody (A00800S330).
Immunohistochemical analysis of paraffin-embedded Human colon cancer. Antibody was diluted at 1:100 (4°CProtein Target Info & Infographic
Gene/Protein Information For PSEN2 (Source: Uniprot.org, NCBI)
Gene Name
PSEN2
Full Name
Presenilin-2
Weight
50.14kDa
Superfamily
peptidase A22A family
Alternative Names
AD3LP; AD4AD3L; AD5; E5-1; EC 3.4.23; EC 3.4.23.-; presenilin 2 (Alzheimer disease 4); Presenilin2; Presenilin-2; PS-2; PS2CMD1V; PSEN2; PSNL2; STM2STM-2 PSEN2 AD3L, AD4, CMD1V, PS2, STM2 presenilin 2 presenilin-2|AD3LP|AD5|Alzheimer disease 4|E5-1|PS-2|STM-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PSEN2, check out the PSEN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PSEN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Presenilin 2 (S330) PSEN2 Antibody (A00800S330)
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No publications found for A00800S330
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